Summary: Despite prolific efforts to characterize the antibody response to human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) mono-infections, the response to chronic co-infection with these two ever-evolving viruses is poorly understood.Here, we investigate the antibody repertoire of a chronically HIV-1/HCV co-infected individ
Analysis of Criticism of Newspaper by Jokowi & Joe Biden regarding the Development of Covid-19 in the IDN Times and NY Times Online Media: Cross-Cultural Pragmatic Studies
The research entitled "Analysis of Criticism of Newspaper by Jokowi & Joe Biden regarding the Development of Covid-19 in the IDN Times and NY Times Phase 2a randomised controlled feasibility trial of a new ‘balanced binocular viewing’ treatment for unilateral amblyopia in children age 3–8 years: trial protocol Online Media: Cross-Cultural Pra
Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP
ABSTRACT Antibiotic acyldepsipeptides (ADEPs) deregulate ClpP, the proteolytic core of the bacterial Clp protease, thereby inhibiting its native functions and concomitantly activating it for uncontrolled proteolysis of nonnative substrates.Importantly, although ADEP-activated ClpP is assumed to target multiple polypeptide and protein substrates in